Skin Cancer Algorithm - Differential Diagnoses of Skin/Yellow Colored Lesions

	alternative diagnoses to reddish colored lesions	alternative diagnoses to brown/black colored lesions

Sebaceous Hyperplasia

• soft, yellowish, slightly raised, often umbilicated
• usually few in number measuring 2-4mm
• face especially forehead and cheeks
• usually middle-aged

Neurofibroma

• frequently sporadic (not associated with neurofibromatosis)
• soft, skin-coloured, slightly tan, elevated papule, sometimes polypoid
• usually 4-5mm and not usually over 1cm

Solar Elastosis

• older individuals, fair skinned with chronic sun exposure
• face, forehead usually
• usually patches of thickened yellowish changes - like chicken skin
• may have localized papule which is difficult to distinguish from skin cancer

Solitary Molluscum Contagiosum

• usually multiple skin-coloured waxy lesions
• central dell in multiple lesions
• normally seen in children or sexually transmitted in adults
• occasionally solitary skin-coloured papule often on the face without central depression

Benign Appendigeal Tumours: Trichoepithilioma

• usually solitary lesion but can be inherited and multiple
• skin coloured firm papule usually 2-8mm
• a ring of small whitish cyst on the periphery of the lesion

Benign Appendigeal Tumours: Syringoma

• usually in women
• may be solitary but usually multiple
• skin-coloured to yellowish small papule 2-5mm
• commonly on the upper cheeks or lower eyelids
• less common on abdomen and vulva

Leiomyoma

• may be skin colored papules when solitary
• most frequently a center of red brown tender papules, occasionaly painful

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